Metastatic Prostate Cancer Prognosis Calculator

Prostate cancer is a malignant growth of a walnut-shaped male organ called the prostate.

Prostate cancer is currently the 2nd most common neoplasm worldwide — the disease is diagnosed in over 1,200,000 men every year. The statistic says that 1 in 9 American males will develop prostate cancer at some point in their lives.

➡️ We also have some good news — more than 98% of prostate cancer patients will survive at least 10 years.

Prostate cancer risk factors:

• Old age;
• African-American race;
• Family history of prostate/breast/ovarian cancer, especially at a young age;
• Obesity; and
• Cigarette smoking.

How do we diagnose prostate cancer?

1. For people with no specific signs or symptoms:

   • For screening, we use the Prostate Specific Antigen test — we check both PSA doubling time and PSA density.
   • Per rectum examination — a doctor needs to examine the patient's anus and prostate using their pointing finger.

2. For people with signs/symptoms or suspicious screening results:

   • Transanal ultrasound — for assessment of the prostate structure.
   • Prostate biopsy for assessing the grade of the neoplasm, using the Gleason Score.

Would you like to know more? Discover our articles on:

• EORTC bladder cancer risk calculator; and
• Lung cancer risk calculator for smokers.

We assess Prostate cancer progression with the TNM staging system.

We distinguish 4 major stages of prostate cancer:

As we can see, the survival and life expectancy of a patient with stages T1-T3 are not that different from the general population. Majority of prostate cancer patients will die of another reason than the neoplasm itself.

Stage 4 prostate cancer life expectancy depends on the presence of metastases — fragments of cancer that have spread to other organs of the body, outside of the pelvis.

♦️ Metastatic prostate cancer life expectancy.

• Cancer with metastases is automatically a Stage 4 cancer.
• In this case, stage four prostate cancer survival rate equals 31% — it means that only 1/3 of patients with metastases will survive another five years.

The numbers presented above are calculated for a general population of prostate cancer patients, and they include all possible stages of the disease.

5-year survival

• Nearly 100%

10-year survival

• Nearly 98%

15-year survival

• Nearly 95%

Our tool requires only seven steps:

• Enter your age, weight, and height

  The calculator will compute your BMI and risk associated with age.

• Enter your Gleason score

  Your result obtained during the prostate biopsy — a smaller score usually bears a better prognosis.

• Are there any distant metastases?

  Has cancer spread outside of the prostate and the seminal vesicles? The presence of distant metastases decreases survival rates.

• Assess your health level

  Do you suffer from any chronic disease? Did you have any critical operations? Are you dependent on other people? How would you describe your health, comparing it to the other people (colleagues, friends) from your age group? Think of all these questions and decide which group suits you best.

• Are you a smoker?

  Smoking increases the risk of multiple types of cancer, including nasopharyngeal, lung, and urinary bladder neoplasms.

Our prostate cancer life expectancy calculator is based on a mathematical model that includes results of multiple studies: Zhang et al, 2015, Huncharek et al, 2010, Albertsen et al, 2005, Preston, 2011, as well as Social Security Actuarial Life Tables.

Here, we present some of the data that modify the life expectancy presented in Actuarial Life Tables:

1. Gleason Score

   Higher Gleason score is correlated with greater mortality rate.

2. BMI

   Obesity, described as BMI ≥ 30, is one of the known factors that decrease longevity in the general population — this disease "steals" on average 1.85 years of life from every obese American.

   We are also aware that obesity correlates with an increased risk of aggressive prostate cancer (relative risk (RR) 1.14; 95% CI, 1.04–1.25) and its greater mortality rate (RR, 1.24; 95% CI, 1.15–2.33).

💡 BMI is calculated with the following formula: weight/height², using kilograms and meters.

3. Smoking

   Smoking increases the prostate cancer mortality rate. The relative risk of death connected to this neoplasm is equal to 1.14 (95% CI = 1.06-1.19). Some of the heaviest smokers have even 30% more chances of dying from this kind of cancer.